The Mueller Sports Medicine Thermo Reactive 4-Way Stretch Ankle Support provides all-day moderate support for sore or injured ankles. The soft, breathable and lightweight 4-way stretch fabric moves with you for extra comfort. Made with thermo reactive technology, it regulates skin temperature and blood flow for an improved recovery time. This ankle support provides 360 degrees of targeted compression that is latex-free. To clean, hand wash in cold water with mild detergent. Do not use bleach or fabric softener. Rinse thoroughly and air dry. Includes one ankle support that fits right or left ankle. Sizing: Small/Medium - Men's US Shoe Size 5-9 | Women's US Shoe Size 6-10. Medium/Large - Men's US Shoe Size 9-13 | Women's US Shoe Size 10 to 14. Large/X-Large - Men's US Shoe Size 13-17 | Women's US Shoe Size 14-18.